MANCHESTER, England — Sergio Aguero and Kevin De Bruyne have been ruled out of Manchester City’s trip to Chelsea on Saturday.

Aguero has missed City’s last two Premier League matches with a muscle injury while De Bruyne has missed more than a month with a knee issue and neither will be risked at Stamford Bridge.

“Both cannot play tomorrow,” Guardiola told a news conference. “Soon both of them will be back.”

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City have coped without the pair well and are looking for their eighth successive win in the Premier League, while Guardiola has beaten Chelsea boss Maurizio Sarri three times in the past 12 months — twice with Napoli and once vs. Chelsea in the Community Shield at the start of the season.

The Italian coach says the Premier League leaders are “the best team in Europe and maybe the world” ahead of the fixture although Guardiola doesn’t agree.

“Thank you but we are not the best,” the City boss said about Sarri’s statement. “To be the best you have to win titles and we did not win the title to be the best team in Europe.

“The job [Sarri] has done so far has been excellent, people don’t know how difficult it is to create a special way to play and he needs time everybody needs time. Apart from the last two games — Tottenham and Wolves are always so difficult and this can happen in this league.

“During preseason we played against them in the Community Shield, they were there, already it was his team. Maybe they are not playing good for 90 minutes but for the 50, 60, 70 minutes they are excellent.”

Chelsea are the last of the current top-five sides that City face away from home and avoiding defeat would hugely increase their chances of remaining unbeaten for the season.

“I don’t care about that,” Guardiola said of an ‘Invincible’ season. “It’s the less important thing, the most important thing is what we have to think about. The target is to play good in the next game.”